Sleep Disorders Treatment When to Use Afrin for Nasal Congestion Afrin is an over-the-counter nasal decongestant spray By Brandon Peters, MD Updated on July 02, 2023 Medically reviewed by Brian T. Luong, DMD Print Table of Contents View All Table of Contents Uses Warnings and Contraindications Side Effects and Risks If It Doesn't Help Afrin is a decongestant sold over-the-counter (OTC) in the form of a nasal spray. Its generic name is oxymetazoline nasal. Afrin is sprayed in the nostrils to give temporary relief from nasal congestion caused by allergies or colds. This explains how Afrin works, some of the common side effects of Afrin, and why using too much Afrin or using it for a long time can lead to rebound congestion. Karl Tapales / Moment / Getty Images What Causes Nasal Congestion? What Is Afrin Used For? Afrin is a decongestant medication used to reduce nasal and sinus stuffiness. It's commonly used to treat congestion from the common cold or allergies. Being congested can also cause difficulty breathing through your nose while you're sleeping and may contribute to snoring or sleep apnea. Afrin can help with these symptoms. How Afrin Works Afrin comes in a squirt bottle that you can spray into your nostrils. It stimulates receptors in the smooth muscle of the blood vessels in the nose and makes them narrow (constrict). When the blood vessels constrict, it reduces nasal congestion. What to Do if You Overdose on Afrin If you think you have used too much Afrin, call Poison Control at 1-800-222-1222. If someone has overdosed on Afrin and is not breathing, call 911. What Is Rebound Congestion? Who Should Not Use Afrin Some people should not use Afrin, including Children younger than 6 years oldPeople who are pregnantPeople who have taken an antidepressant called a monoamine oxidase inhibitor (MOAI) within the last 14 days If you have these health conditions, talk to your provider before you use Afrin: High blood pressure Heart disease Thyroid disease Diabetes mellitus Trouble urinating or an enlarged prostate Glaucoma You may need to avoid using Afrin if you take certain medications. Talk to your provider about Afrin if you are taking: Antidepressants, such as desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil)Linezolid (Zyvox)MAO inhibitors, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Emsam, Eldepryl), and tranylcypromine (Parnate)MaprotilineReserpineStimulants, including ephedra and yohimbe, caffeine, and diet pillsOther cough, cold, or allergy medications How Saline Sprays Relieve Nasal Congestion Afrin Side Effects Afrin can cause side effects. Most of them are not serious and will go away as soon as you stop using the medication. You may feel mild stinging in your nose when you first use Afrin, but this should go away after using it a few times. Other common side effects include: Nose dryness and irritation Sneezing Headache Sore throat Restlessness Trouble falling or staying asleep It's less common, but there are also some potentially serious side effects of Afrin that require medical attention, including: Irregular heartbeats (arrhythmias) Chest pain (angina) Lightheadedness Hallucinations or unusual behavior Seizure Blurred vision Weakness Trouble urinating Afrin is meant to provide short-term relief. You cannot get addicted to Afrin the way you can get addicted to other drugs. However, if you use Afrin too often, you use too much, or you use it for longer than a few days, it can cause your congestion to get worse (rebound congestion). Is Afrin Addictive? Rebound congestion, also called rhinitis medicamentosa, can lead to physical dependence when it causes a person to use Afrin long-term to treat their worsening symptoms. This physical dependence is often referred to as Afrin addiction, and is typically treated by discontinuing use of the drug. When to Worry About Nasal Congestion If Afrin Does Not Work Afrin is safe and effective when it's used properly. If your symptoms are not improving after you've used Afrin according to the directions, you'll need to talk to your provider about other treatments. For example, if you have chronic nasal congestion, prescription therapy with the use of a nasal corticosteroid can be helpful. Summary Afrin is a common decongestant medication used to treat cold and allergy symptoms. It is sold over-the-counter (OTC). While Afrin can be a safe and effective treatment for nasal congestion when it is used according to the directions, overusing Afrin can lead to rebound congestion. If you have been using Afrin for three days and it hasn't helped your symptoms, stop using it and let your provider know. You might need a different treatment, like nasal steroids, for your congestion. Using Nasal Steroids for Congestion 3 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. National Library of Medicine. Oxymetazoline Nasal Spray. Afrin. FAQs. Poison Control. Is Afrin addictive?. By Brandon Peters, MD Dr. Peters is a board-certified neurologist and sleep medicine specialist and is a fellow of the American Academy of Sleep Medicine. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit