Secondary Causes of Restless Leg Syndrome

By Brandon Peters, M.D., About.com Guide

Updated June 14, 2010

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

There is a growing body of evidence that multiple sclerosis seems to be associated with an increased risk of RLS. Some of the studies are conflicting, however. In one of the larger studies that included 1,500 subjects, the prevalence of RLS was 19 percent in people with MS compared to only 4 percent of those people without it.

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